The 92122 zip code covers a very large area that spreads across 15.9 sq. miles. Estimated population in 2016 was 47,992 with 69% being renters. Houses and condos in 92122 zip code are about 21,581 while there is 13,783 renter occupied apartments. You will find Interstate 5 on the west boundary and 805 on the east boundary as well as freeway 52 on the southern boundary line. Main area of town is called University City with a small part of La Jolla Village coming in on the northwest side of town.